Antibodies are having a huge impact in basic and translational research, but they are also in crisis. Francesca Lake investigates. Due to their high specificity and selectivity, antibodies hold great potential for use in the life sciences, in everything from basic research to diagnostics and therapeutics. Since the 1970s when Köhler and Milstein produced hybridoma monoclonal antibodies (mAbs) through the fusion of antibody-producing mouse spleen cells with an immortal myeloma cell line, multiple research projects have utilized antibodies and it has been estimated that there are over 300 companies offering 2 million antibodies for research purposes. Click Here For Complete Article Text
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